Nucleofill is an advanced bio-stimulator that contains purified and natural polynucleotides.


This treatment helps to enhance the volume of the face and provides effective skin rejuvenation as well as deep hydration. In addition, it acts as a skin healer as it stimulates fibroblasts and growth factors. And so, it fights fine lines and wrinkles and improves the skin quality from within.


Furthermore, Nucleofill restores the extracellular matrix by activating the skin’s self-regenerating abilities while improving the overall skin condition.


Unlike other injectables, Nucleofill is neither a filler nor a muscle-relaxing agent. This innovative treatment helps rejuvenate the skin from within and is highly efficacious in treating external injuries caused by UV and other damages caused by oxidative stress.


In short, this is a new skin booster and skin healer you will truly love!


The effect of Nucleofill


The active ingredient of  Nucleofill has a triple action on your skin:

  • Lifting,
  • Antioxidant,
  • and deep Hydration:


1) Lifting: The first course of action is the receptor of fibroblasts in the skin. Through this stimulation,  the production of type I collagen & elastin increases. As a consequence, Nucleofill helps thicken and lift the skin.


2) Antioxidant: The second effect is the “scavenging” of free radicals and antioxidant activity. As a result, it protects from oxidative stress damages (pollution, sun exposure, smoking, poor diet).


3) Hydration: Finally, the Polynucleotides bind water giving deep hydration and leaving the skin moisturized and supple.

Benefits of Nucleofill


Nucleofill is suitable for all skin types and all ages:


  • Visible rejuvenating effect without affecting facial features;
  • Reduces the appearance of wrinkles and creases;
  • Firms the skin;
  • Betters loose skin with poor circulation;
  • Enhances skin tension;
  • Rehydrates skin;
  • Diminishes oxidative stress;
  • Improves stretch marks & Scars;
  • Beneficial for those who want more firming, contouring, and definition;
  • Anti-ageing: Bio-stimulation and increase in collagen type 1.




  • cancer;
  • pregnancy;
  • breastfeeding;
  • blood coagulation disorders;
  • tendency to the formation of hypertrophic scars;
  • herpes and other viral infections;
  • fungal and bacterial skin infections;
  • skin inflammations.


Side effects


  • Light bruising may occur;
  • Possible slight swelling in the injection area;
  • No other side effects have been reported.




Most patients notice visible improvement with one session. This said, we recommend having 2 treatments with 2-4 weeks in between each session for optimal results.


On a side note, discover the benefits of Nucleofill Eye should you want to improve the delicate under-eye area.


Time: 30-45 mins

Nucleofill for Skin
1 Session
2 Session