
Profhilo® is an injectable hyaluronic acid treatment designed to improve skin hydration, elasticity and overall skin quality without creating the volume or facial contour associated with traditional dermal fillers.
At NAR LONDON on Harley Street, we use Profhilo for patients who want their skin to look fresher, smoother and better hydrated while still looking completely like themselves.
Rather than changing facial features, Profhilo works within the skin. Its stabilised hyaluronic acid formulation spreads through the treated tissue, providing hydration while supporting the biological processes associated with skin remodelling.
It can be particularly useful when skin begins to feel dry, crepey, less elastic or less luminous, including on areas that can be difficult to treat with conventional injectables.
Treatment time: approximately 30 minutes
Typical protocol: 2 treatments approximately 4 weeks apart
Downtime: usually minimal
Treatment areas: face, neck and other suitable areas following consultation
Price: £395 per treatment | £700 for 2 treatments
Location: NAR LONDON, 15 Harley Street, London W1G 9QQ
Profhilo is an injectable treatment based on stabilised hyaluronic acid (HA).
Hyaluronic acid occurs naturally within the body and plays an important role in retaining water within the skin. Its presence declines and skin biology changes with age, contributing to dryness, reduced elasticity and changes in skin texture.
Profhilo is different from conventional hyaluronic-acid dermal fillers. A dermal filler is generally placed strategically to create or restore volume, projection or structural support. Profhilo is primarily used to improve the quality of the skin itself.
This distinction matters.
If you want a larger cheekbone or additional chin projection, Profhilo is unlikely to be the appropriate treatment.
If instead you are thinking:
“My skin looks tired, dry or crepey and I want it to look healthier without changing my face.”
Profhilo may be worth considering.
After injection, Profhilo distributes through the surrounding tissue rather than remaining concentrated in one location like many conventional fillers.
The treatment combines two complementary effects:
1. Hydration
Hyaluronic acid has a strong affinity for water. Profhilo therefore helps improve hydration within the treated skin.
Patients may notice that the skin gradually appears smoother, fresher and more luminous.
2. Bio-remodelling
Profhilo is also designed to interact with the skin’s extracellular environment and support processes associated with collagen and elastin remodelling.
This is why Profhilo is generally described as a bio-remodelling treatment rather than simply an injectable moisturiser.
The objective isn’t to make your face look different. It is to help the skin behave and look better.

Profhilo may be considered when the primary concern is declining skin quality rather than facial volume.
Depending upon the individual, treatment may help improve the appearance of:
The result should be subtle.
You shouldn’t look as though you’ve “had something done.”
The aim is healthier-looking, more hydrated and more resilient skin.
There isn’t a particular age at which somebody suddenly “needs” Profhilo.
Suitability depends much more on skin quality, anatomy and what you want to achieve.
Younger patients sometimes choose Profhilo when dehydration, dullness or early changes in skin quality are their main concern.
For patients in their 40s, 50s and beyond, Profhilo can form part of a broader skin-rejuvenation strategy where improving hydration and skin quality is the objective.
However, Profhilo cannot correct every sign of facial ageing. If significant volume loss, pigmentation, pronounced laxity, scarring or another concern is responsible for what you see in the mirror, another treatment – or a combination of treatments – may be more appropriate.
This is why we assess the skin rather than simply recommend the product.
The face is the most recognised treatment area.
For suitable patients, Profhilo can improve overall hydration and skin quality without deliberately changing facial contours.
The neck is particularly prone to dehydration, fine lines and crepey texture.
Because traditional volumising fillers are not always appropriate for diffuse neck ageing, Profhilo can be an interesting option when the objective is improved skin quality rather than volume.
Profhilo formulations and protocols can also be used for selected areas of the body. Please click here for Profhilo Body.
Treatment begins with an assessment of your skin, medical history and objectives.
For facial Profhilo, a commonly used approach is the Bio Aesthetic Points (BAP) technique.
This involves carefully selected injection points on each side of the face designed to allow the product to distribute through the relevant tissues while avoiding important anatomical structures.
The injections themselves are relatively quick.
Small raised areas can temporarily be visible at the injection points immediately afterwards. These typically settle as the product disperses.
The entire appointment usually takes around 30 minutes.

Profhilo® is an injectable hyaluronic acid treatment designed to improve skin hydration, elasticity and overall skin quality. Unlike a traditional dermal filler, it is not primarily used to add volume or reshape facial features. Instead, Profhilo spreads through the tissue and supports skin bioremodelling.
No. Although Profhilo contains hyaluronic acid, it behaves differently from conventional dermal fillers. Fillers are generally placed strategically to restore volume, contour or enhance particular facial features. Profhilo is injected at specific points and disperses through the surrounding tissue, making it particularly suitable for patients seeking a subtle improvement in skin quality without changing the shape of their face.
Profhilo can help improve hydration, elasticity, firmness and skin texture. Many patients choose it when their skin begins to look dehydrated, crepey, dull or less resilient.
Profhilo contains a high concentration of stabilised hyaluronic acid combining high- and low-molecular-weight HA. Once injected, it gradually disperses through the tissue.
Alongside its hydrating properties, Profhilo is used for its bio-remodelling activity and its ability to support processes associated with collagen and elastin production.
For facial treatment, Profhilo is commonly administered using the BAP (Bio Aesthetic Points) technique, involving five carefully selected injection points on each side of the face.
These points are designed to allow the product to diffuse efficiently while avoiding important anatomical structures.
All Profhilo treatments are performed by our trained practitioner on-site at our private clinical space at 15 Harley Street, easily accessible to patients travelling from Marylebone, Mayfair, and Soho.
The standard initial protocol is usually two treatments approximately four weeks apart.
The appropriate programme can vary according to age, skin quality and treatment goals. Maintenance treatments may subsequently be recommended to help sustain the improvement.
Some patients notice improved hydration relatively early, while changes in elasticity, texture and overall skin quality tend to develop more gradually.
Results are usually assessed after completing the initial treatment course rather than immediately after the first appointment.
Results vary between individuals and depend on factors including age, skin condition, lifestyle and metabolism. Improvements can typically remain noticeable for several months, after which maintenance treatment may be considered.
Profhilo is not designed primarily to create facial volume in the way a dermal filler does. This is one reason it appeals to patients who want better skin quality while maintaining their natural facial proportions and expressions.
Both can improve hydration and skin quality, but they are not identical treatments. Profhilo has a specific formulation of high- and low-molecular-weight hyaluronic acid and is particularly associated with bioremodelling and tissue hydration.
Other injectable skin boosters may contain different forms of hyaluronic acid or additional ingredients and may be administered using different techniques. The best option depends on what you are trying to improve.
Neither is universally “better”.
Profhilo is particularly attractive when hydration, elasticity and general skin quality are the priorities.
Polynucleotides, including treatments such as Rejuran, are used with a greater emphasis on regenerative skin-quality improvement and may be selected for concerns such as fine lines, texture and delicate areas.
At NAR LONDON, treatment is selected according to the condition of your skin rather than simply choosing whichever injectable is currently most popular.
Potentially, yes. Profhilo may form part of a broader skin-rejuvenation programme alongside treatments such as PRF, polynucleotides and other regenerative approaches.
However, more treatment is not automatically better. The combination and timing should be determined according to your skin, goals and suitability.
Yes. The neck is a popular treatment area because Profhilo can be used where the skin has become dehydrated, crepey or less elastic.
Depending on the individual, other areas such as the décolletage and hands may also be considered.
There is no single “correct” age. Profhilo should be chosen according to skin condition rather than age alone.
Younger patients may seek improved hydration and early skin-quality support, while more mature patients may use Profhilo as part of a programme addressing increasing laxity, dehydration and declining elasticity.
Most patients find the treatment manageable. You will feel a series of small injections, and there may be brief stinging or tenderness at the injection sites.
Small raised bumps can be visible at the injection points immediately after treatment. These usually settle as the product disperses. Mild redness, tenderness, swelling or bruising can also occur.
Downtime is generally limited, but it is not accurate to promise “no downtime.” Temporary bumps, redness, swelling, tenderness and occasional bruising are possible. Our practitioner will provide appropriate aftercare instructions following treatment.
Profhilo has an established history of use in aesthetic medicine, but it remains an injectable medical-aesthetic procedure and therefore carries risks.
Possible adverse effects include redness, swelling, tenderness, bruising and injection-site reactions. Less common but potentially serious complications can occur with injectable treatments, which is why appropriate patient selection, anatomical knowledge and professional treatment are important.
Profhilo may not be appropriate during pregnancy or breastfeeding, in the presence of active infection or inflammation around the treatment area, or for some people with particular medical conditions, allergies or medications. A consultation and medical history will therefore take place before treatment.
Profhilo prices in London vary according to the clinic, practitioner, treatment area and number of sessions required. Appropriate assessment, genuine product, injection technique, treatment planning and aftercare are all important considerations when choosing a Profhilo practitioner.
NAR LONDON provides Profhilo treatments on Harley Street in Central London, with treatment plans tailored to the patient’s skin quality, concerns and desired outcome. All Profhilo treatments are performed by our trained practitioner at our regenerative aesthetic clinic on 15 Harley Street, W1G 9QQ – easily accessible to patients travelling from Marylebone, Mayfair, and Soho.
Our philosophy is centred on beautiful rejuvenation rather than changing the way you look:
Regenerate. Restore. Reveal You.